Although the options are not provided, the statement best describing the relationship is nucleic acids provide blueprints for the construction of proteins.
Messenger RNA molecules (mRNA) take instructions from DNA molecules and take the code out of the nucleus. There, ribosomes work with the RNA molecules to produce a chain of amino acids, which in turn links and folds in a specific manner to form a protein molecule.
The major relationship between protein and nucleic acid is the reproduction of DNA which contains the information on how cells are used together with RNA which helps to make protein. Both nucleic acid and protein they have four biomolecules which are common in both of them.
DNA has all of our genetic information that is used during protein synthesis.